Cyanokit

Cyanokit® in practice

A RECOMMENDED CYANIDE ANTIDOTE FOR ALL AGE RANGES1,2

Treatment of known or suspected cyanide poisoning in all age ranges.1

Cyanokit® is to be administered together with appropriate decontamination and supportive measures.1

Posology

Initial dose1

Adults: the initial dose of Cyanokit® is 5 g (200 mL, complete volume of reconstituted solution).

Paediatric population: in infants to adolescents (0 to 18 years old), the initial dose of Cyanokit® is 70 mg/kg body weight not exceeding 5 g.

Body weight in kg 5 10 20 30 40 50 60
Initial dose in g 0.35 0.70 1.40 2.10 2.80 3.50 4.20
in mL 14 28 56 84 112 140 168

Subsequent dose1

Depending upon the severity of the poisoning and the clinical response, a second dose may be administered.

Maximum dose1

For adults, the maximum total recommended dose is 10 g and for infant and adolescents (0 to 18 years old) the maximum total recommended dose is 140 mg/kg not exceeding 10 g.

Bibliography

1 – Cyanokit® Summary of Product Characteristics
2 – RCEM NPIS Antidote Guideline List January 2017 – 1