Cyanokit
A RECOMMENDED CYANIDE ANTIDOTE FOR ALL AGE RANGES

Cyanokit® in practice

A RECOMMENDED CYANIDE ANTIDOTE FOR ALL AGE RANGES1,2

Treatment of known or suspected cyanide poisoning in all age ranges.1

Cyanokit® is to be administered together with appropriate decontamination and supportive measures.1

Method of administration1

Cyanokit® is administered as an intravenous infusion :

  • For the initial dose : over 15 minutes
  • For the second dose based on patient condition (from 15 minutes to 2 hours)

Diluent

The vial is to be reconstituted with 200 mL of diluent using the supplied sterile transfer device:

  • Sodium chloride 9 mg/mL (0.9%) solution for injection is the recommended diluent.
  • Only if sodium chloride is not available:
    Lactated Ringer solution or glucose 50 mg/mL (5%) solution.

Reconstitution in 3 steps:

Reconstitution in 3 steps
  • 1

    Reconstitute each vial with 200mL of diluent using the supplied sterile transfer device.

  • 2

    Rock or invert the vial for at least one minute to mix the solution. It must not be shaken as shaking the vial may cause foam and may make checking reconstitution less easy.

  • 3

    Connect the reconstituted solution with the intravenous infusion set provided in the kit.

Bibliography

1 – Cyanokit® Summary of Product Characteristics
2 – RCEM NPIS Antidote Guideline List January 2017 – 1